KOMP 312 Project Gene Information

Lyplal1

Name:	lysophospholipase-like 1
Resources:	MGI:2385115 NCBI:226791 PubMed, Gene Cloud, Additional resources at KOMP
Products:	vector, ESC, sperm

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Physical Exam- head

Ear - left

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	discharge
	damaged pinna
	misshapen pinna
	other

Ear - right

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	misshapen pinna
	other
	discharge
	damaged pinna

Eye - left

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	squinting
	discharge
	encrusted
	other
	exopthalmia
	abnormal lacrimation
	opaque

Eye - right

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	squinting
	discharge
	encrusted
	other
	exopthalmia
	abnormal lacrimation
	opaque

Eye color - left

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	black
	red
	other
	pink

Eye color - right

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	black
	red
	other
	pink

Head shape

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	flattened
	other

Nose & snout

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	dry
	nasal discharge
	other
	short
	cracked
	blood

Respiration

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	rapid
	irregular
	other
	gasping
	slow

Whiskers

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	barbered
	other
	missing

Physical Exam- body & back

Body shape & size

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	stunted
	emaciated
	dwarf
	other

Coat color - back

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	black
	other
	agouti

Fur - back

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	alopecia
	rough
	other
	scruffy
	oily

Hair type - back

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	long
	other

Tail

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	abnormal, short
	kinky
	snipped for DNA
	abnormal, long
	other

Physical Exam- limbs and joints

Claws

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	missing
	discolored
	misshapen
	other

Forelimb - left

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	injured
	other
	sensitive

Forelimb - right

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	injured
	other
	sensitive

Hindlimb - left

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	injured
	other
	sensitive

Hindlimb - right

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	injured
	other
	sensitive

Joints (knee & ankle)

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	swollen
	other
	sensitive

Spine

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	straight
	curved (lordosis)
	other
	Humped (kyphosis)

Physical Exam- abdomen

Abdomen

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	other
	distended
	sensitive to palpation

Anus

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	inflammed perineum
	prolapsed
	encrusted
	discharge
	other

Coat color - belly

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	black
	other
	agouti

Genitals - female

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	anogenital region wet
	vaginal inflammation
	vaginal exudate
	missing
	prolapsed vagina
	urethral inflammation
	urethral exudate
	other

Genitals - male

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	urogenital region wet
	urethral inflammation
	urethral exudate
	missing
	external penis
	other

Mammary glands exam

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	swollen
	other
	discharge

Skin appearance

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	normal
	thickened, irritation
	irritated inflammed
	other

Physical Exam- Pathology

Lesion description

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	none
	scratch
	necrotic, > 5mm diameter
	> 5mm diameter
	scrape
	abrasion
	scarred
	< 5mm diameter

Lumps - masses description

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	n/a
	soft, < 5mm diameter
	other
	> 5mm diameter, soft
	< 5mm diameter

Lumps - masses location

HET

HOM

WT Littermate

WT Pop

20%

40%

60%

80%

100%

	n/a
	(give anatomical location)

The KOMP Phenotyping Project is funded by an ARRA grant to UC Davis and CHORI.

Questions? Comments? Please contact us: 1-888-KOMP-MICE or service@komp.org