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Description: Bacterial lipopolysaccharide (LPS) is an endotoxin, a potent inducer of the acute phase response and systemic inflammation. The mice will: Be injected intraperitoneally (i.p.) with a sublethal dose of LPS in 200 uL sterile saline using a 26 gauge needle. The dose will be based on the average weight of the mice tested at 1 g/g body weight 3 hours after injection, a 100ul blood sample will be taken and analyzed for the presence of TNFa, MCP-1, and IL-6 on the FACSCalibur.
Measurements: IL-6, MCP-1, TNF-a
Currently displaying Acute Phase Response quantile exceptions at 95%
The KOMP Phenotyping Project is funded by an ARRA grant to UC Davis and CHORI.
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